Paraneoplastic Neuronal Antibodies (Blood & CSF)

Testing Laboratory

Auckland Te Toka Tumai | Auckland Hospital

Department

Immunology

Delphic Registration Code (Alpha Code)

PNSP

Test Code (Numeric Code)

8491

Laboratory Handling

Phlebotomy

CSF, Serum

Transport

Ambient (8 - 24 °C) within 48 hours; Chilled (4 - 8 °C) if longer than 48 hours

Registration

PNSP

Laboratory

Labplus Autoimmune Serology

Sample Stability

Up to 48 hours: 8 - 24°C; Up to 14 days: 4 - 8°C; Up to 6 months: -30°C; Indefinite at - 80°C

Synonyms

Paraneoplastic antibody panel
Onconeuronal Antibodies
Amphiphysin, CV2 (CRMP5), Ma2/Ta, Ri (ANNA-2), Yo (PCA-1), Hu (ANNA-1), GAD65, DNER (Tr)
GFAP

Turnaround Time

4 weeks

This test may be vetted by the laboratory. Please include relevant clinical information on the request form to ensure appropriate tests are approved. See the 'Clinical Information' section below for more information on the indications for testing.

Specimen Type

  • CSF
  • Serum

Specimen Requirements

Tube/Container Type:

Preferred
  • SST II (Gold Cap)
Acceptable
  • CSF sterile tubes (Routine Analysis)
  • Plain (Red Top)
Preferred Sample Volume (ml)

3.5

Minimum Sample Volume (ml)

1

No of Samples Required

1

Paediatric Specimen Requirements

Tube/Container Type:

Preferred
  • SST II (Gold Cap)
Acceptable
  • CSF sterile tubes (Routine Analysis)
  • Plain(Microtainer)
  • SST(Microtainer)
  • Plain (Red Top)
Minimum Sample Volume (ml)

1

Pre-testing Requirements

All patients referred for neuronal autoantibody testing must have been discussed with or reviewed by a neurologist; the name of the neurologist must appear on the request form. Testing will be deferred on all specimens where it is unclear if a neurology review has occurred or not. Urgent requests should be discussed directly with the immunopathologist.

Requests for neuronal autoantibodies must be accompanied by a completed Neuronal Autoantibody Request form. Please print a copy from the link below and complete before sending a sample to the laboratory.

Ensure request form has been scanned as staff need to determine the validity of the request before proceeding.

Additional Specimen Information

CSF specimens will be assayed but the preferred appropriate specimen for this panel of antibodies is SERUM.

Last updated: 14/08/2026