HER2 FISH

Testing Laboratory

Auckland Te Toka Tumai | Auckland Hospital

Department

Diagnostic Genetics

Delphic Registration Code (Alpha Code)

DGEN

Test Code (Numeric Code)

4218

Laboratory Handling

Sample Stability

NA

Synonyms

HER2, ERBB2, Breast Cancer, Gastric Cancer

Turnaround Time

5 days

Specimen Type

  • Tissue

Specimen Requirements

Tube/Container Type:

Preferred
  • Please refer to Additional Information below
  • Slide(s)
Acceptable
  • Please refer to Additional Information below
  • Slide(s)
No of Samples Required

6

Paediatric Specimen Requirements

Tube/Container Type:

Preferred
  • Please refer to Additional Information below
  • Slide(s)

Additional Specimen Information

Specimen Requirements:
6 x slides of ~4 um thickness Paraffin embedded tissue.
1 x H&E stained slide with the area of interest marked.

Requests for FISH HER2 testing:

Requests for FISH testing can be made using the Diagnostic Genetics request form found on the Lab Plus website and Test Guide.

All specimens sent must be accompanied by the following:

Two forms of matching identification on both the slides and the form .
If these do not match, LabPlus policy requires a specimen labelling error form to be sent to the clinician,
and although the specimen may be processed, a result will not be released until the form is received back.

A marked H+E slide with the area/s to be targeted
If multiple areas are targeted, please indicate whether they need to be analyzed separately.

An IHC HER2 slide with the area of highest intensity staining targeted if staining is not uniform

A copy of the pathology report

Additional relevant information .
This includes whether the specimen has been decalcified or has undergone additional histological processing,
areas of different morphology within the tumour sample, and the presence of more than one tumour within the sample.

Failure to include relevant information may result in a reporting delay, as consultation with LabPlus pathologists may be required.

*In case of an equivocal FISH result, the report will not be released without IHC score.

All specimens for FFPET FISH should be processed through a Histopathology laboratory.

Last updated: 26/08/2026