Thyroglobulin (Blood)

Testing Laboratory

Auckland Te Toka Tumai | Auckland Hospital

Department

Chemical Pathology

Delphic Registration Code (Alpha Code)

STG

Test Code (Numeric Code)

3038

Laboratory Handling

Sample Stability

14 days at 15-25°C, 14 days at 2-8°C, 24 months at -20°C

Synonyms

Serum Thyroglobulin

Turnaround Time

1 day

Specimen Type

• Serum

Specimen Requirements

Tube/Container Type:

Preferred

• SST II (Gold Cap)

Acceptable

• Plain (Red Top)

Preferred Sample Volume (ml)

4

Minimum Sample Volume (ml)

3.5

No of Samples Required

1

Paediatric Specimen Requirements

Tube/Container Type:

Preferred

• Plain(Microtainer)

Preferred Sample Volume (ml)

0.5

Minimum Sample Volume (ml)

0.5

Pre-testing Requirements

NOTE: It is important to take the baseline specimen before a fine needle aspiration biopsy is performed. Damage to the thyroid gland may elevate thyroglobulin concentrations for at least 3 weeks.

Aliquot Instructions

Sample Type

• Serum

Transport to Lab

Ambient (8 - 24 degrees Celsius)
Frozen

Additional Referral/Aliquot Information

Serum on cells can be analysed up to 48 hours post collection.
Stable for 48h at room temp, 72 h at 2-8°C, or 30 days at -20°C. Freeze once only.
- Send separated serum (at least 300uL).
- Transport at room temp, or frozen if delay is likely to be more than 48 hours.

Test Method

Performed in: LabPlus Automation
Principle: Sandwich type immunoassay with chemiluminescence detection
Reagents: Roche assay
Analyser: Roche Cobas

Uncertainty of Measurement

8%

References:
1. Mazziferri et al. A consensus report of the role of serum thyroglobulin as a monitoring method for low-risk patients with papillary thyroid carcinoma. J Clin Endocrinol Metab. 2003; 88: 1433-41.
2. Pacini F, Schlumberger M, Dralle H et al. European consensus for the management of patients with differentiated thyroid carcinoma of the follicular epithelium. Eur J Endocrinol. 2006;154:787-803

Contact Information