Vancomycin

Testing Laboratory

Auckland Te Toka Tumai | Auckland Hospital

Department

Chemical Pathology

Delphic Registration Code (Alpha Code)

VANC

Test Code (Numeric Code)

0811

Laboratory Handling

Phlebotomy

See below Pre-test requirements

Sample Stability

48 hours at 15-25°C, 14 days at 2-8°C, 12 months at -20°C

Synonyms

Plasma/Serum Vancomycin

Turnaround Time

3 hours

Specimen Type

  • Plasma
  • Serum

Specimen Requirements

Tube/Container Type:

Preferred
  • Lithium Heparin PST- Gel (Light Green Cap)
Acceptable
  • EDTA (Lavender Cap)
  • Lithium Heparin - Non-gel (Green Cap)
  • Plain (Red Top)
  • SST II (Gold Cap)

Paediatric Specimen Requirements

Tube/Container Type:

Preferred
  • Heparin (Microtainer)
Acceptable
  • Plain(Microtainer)
  • SST(Microtainer)

Pre-testing Requirements

Specimen Collection
Sample collection times:
Random Concentration for
Area Under the Curve (AUC)
monitoring

Preferred

Within 24 hours after loading dose
or dose change (at least 1 hour after
the end of the infusion)

Record time the blood was taken

Trough

For neonates or if
AUC monitoring not
available

30 minutes before next dose

Adults
When using the Vanculator dosing and monitoring guide:
After loading dose - Trough level: within one hour before next dose.
Maintenance dose - Trough level: one hour before the fourth maintenance dose is given.
After changing vancomycin dose - Trough level: one hour before the fourth dose following the change in dose.
Paediatrics
Check a trough level before the 4th dose and then every 3 (-5) days if the level is satisfactory and renal function normal.

Additional Specimen Information

4.5 mL PST Blood (Preferred)
Micro-PST 0.5 mL Paediatric Micro-PST Blood (Preferred)
EDTA 4 mL EDTA Blood
Heparin 5 mL Heparin Blood
Plain 4 mL Plain Blood
SST 3.5 mL SST Blood
Microsample 0.5 mL Paediatric Microsample Serum
Micro-heparin 0.6 mL Paediatric Micro-heparin Blood
Micro-SST 0.5 mL Paediatric Micro-SST Serum

Last updated: 31/03/2026