Cholinesterase phenotype (Blood)

Referring Laboratory

SCP - Special Techniques

Testing Laboratory

Department

Diagnostic Genetics, Chemical Pathology

Delphic Registration Code (Alpha Code)

SCSE

Test Code (Numeric Code)

0150

Synonyms

Psuedocholinesterase phenotype, butyrylcholine esterase, choline esterase, scoline apnoea

Specimen Type

• Whole Blood

Specimen Requirements

Tube/Container Type:

Preferred

• EDTA (Lavender Cap)

Preferred Sample Volume (ml)

4

Note that CHL no longer offers cholinesterase phenotyping. Requests for phenotyping will be replaced with cholinesterase activity and genotyping when registered at CHL.

Diagnostic Use and Interpretation:
Activity may be reduced by liver disease, pregnancy, or residual circulating succinylcholine. Specimens should be collected at least 48 hours after the administration of succinylcholine or mivacurium. Patients with acute or chronic liver disease, organophosphate poisoning, chronic renal disease, in late stages of pregnancy, or on oestrogen therapy may have markedly decreased PChE activities.

Laboratory Notes:

Any queries please contact Section Leader/Technical Specialist SCP - Special Techniques

Cholinesterase Phenotype {Sendaway to Christchurch

EDTA - DO NOT SPIN - Fridge

Two points of ID needed - Place AHSND in copy to code box when registering - Two photocopies one for registration one for appropriate sendaway clip, the original form is to be sent with sample.}

Contact Information