Fluorescence In Situ Hybridisation (FISH) – PET FISH (Paraffin FISH)

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Testing Laboratory

Auckland Te Toka Tumai | Auckland Hospital

Department

Diagnostic Genetics

Delphic Registration Code (Alpha Code)

DGEN

Test Code (Numeric Code)

4218

Laboratory Handling

Sample Stability

All specimens for FFPET FISH should be processed through a Histopathology laboratory.

Associated Tests

Synonyms

Fluorescence In Situ Hybridisation,
FISH,
FFPET FISH,
Molecular Cytogenetics

Turnaround Time

18 days

Turnaround time is dependent on the type of test being requested. See 'FISH Probe List' attachment for specific turnaround time. As a general guideline: HER2 (ERBB2) FISH results are available within five working days. Other cases can generally be completed within ten working days, although HGSA guidelines allow 18 days for completion.

Specimen Type

  • Tissue

Specimen Requirements

Tube/Container Type:

Preferred
  • Please refer to Additional Information below
  • Slide(s)
Acceptable
  • Please refer to Additional Information below
  • Slide(s)
No of Samples Required

7

Paediatric Specimen Requirements

Tube/Container Type:

Preferred
  • Please refer to Additional Information below
  • Slide(s)

Pre-testing Requirements

All specimens for FFPET FISH should be processed through a Histopathology laboratory.

Please see attached 'FISH Probe List' for a list of FISH tests.

Additional Specimen Information

6 x slides of ~4 um thickness paraffin embedded tissue.
1 x H&E stained slide with the area of interest marked.

All specimens sent must be accompanied by the following:

A request form with working diagnosis and probe(s) requested.

Two forms of matching identification on both slides and the form.

A marked H+E slide with the area/s to be targeted
If multiple areas are targeted, please indicate whether they need to be analyzed separately.

A copy of the histology report.

Additional relevant information .
This includes whether the specimen has been decalcified or has undergone additional histological processing,
areas of different morphology within the tumour sample, and the presence of more than one tumour within the sample.

In case of an equivocal HER2 (ERBB2) FISH result, the report will not be released without IHC score.

Last updated: 26/08/2026