HBV Drug Resistance Genotyping

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Testing Laboratories

Waitematā | Northshore Hospital
Waitematā | Waitakere Hospital

Department

Microbiology

Delphic Registration Code (Alpha Code)

HVLB and BRES

Test Code (Numeric Code)

2180

Laboratory Handling

Phlebotomy

A dedicated specimen (i.e. no other tests to be performed) is required for this assay. Plasma separated from EDTA whole blood, including EDTA Micro collect tubes, are acceptable

Separating

EDTA tubes must be centrifuged within 6 hours of collection and the plasma transferred to a separate sterile tube. Send a minimum of 1.0 mL of separated plasma.

Sample Stability

Separated plasma are stable at 2–8°C for up to 7 days. If storage exceeds 7 days, plasma should be aliquoted and frozen at ≤−20°C.

Associated Tests

Synonyms

Hepatitis B Virus (HBV) Drug Resistance
HBV Antiviral Resistance
HBV Genotyping
HBV Mutational Analysis
Hepatitis B Resistance Test for Adefovir
Hepatitis B Resistance Test for Lamivudine
Hepatitis B YMDD Gene Mutation
Lamivudine Resistance Test
YMDD
Hepatitis B Drug Resistance Genotyping
Adefovir Resistance Test

Turnaround Time

1 week

Tests performed as required.

Specimen Type

  • Plasma

Specimen Type

  • Whole Blood

Specimen Requirements

Tube/Container Type:

Preferred
  • EDTA (Lavender Cap)
Preferred
  • EDTA (Lavender Cap)
Preferred Sample Volume (ml)

8

Minimum Sample Volume (ml)

4

Paediatric Specimen Requirements

Tube/Container Type:

Preferred
  • EDTA (Microtainer)
Acceptable
  • EDTA (Microtainer)
Preferred Sample Volume (ml)

2

Minimum Sample Volume (ml)

1

Pre-testing Requirements

A recent viral load result obtained within the past month, with a minimum viral load of 3 log₁₀ IU/mL, is required.

Additional Specimen Information

Urgent enquiries:
In normal working hours (08:00-16:00 Mon-Fri) contact Clinical Virology via LabLINK (internal extension 22000, external number 09 307 8995).
Outside of normal working hours (evenings and weekends) contact the On Call Clinical Microbiologist via Te Whatu Ora Te Toka Tumai Auckland main switchboard (09 367 0000).
Non-urgent enquiries:
Email: AK-MOL-INF-DIS@tewhatuora.govt.nz

Last updated: 15/10/2026